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Fact 08 Collagen-driven changes from at-home microinfusion typically emerge at weeks 6 to 8, deepen at months 3 to 6, and require bi-weekly sessions sustained over four to six months

These features make them suitable for elderly patients, those with impaired renal function, and individuals intolerant to other glucose-lowering agents

Importantly, resveratrol upregulates the NKG2D ligand ULBP2 on tumor cells, making them more visible to NK cells and enhancing immunemediated clearance

However, these favorable observations have not translated into consistent clinical efficacy, a limitation that is discussed in the forthcoming sections